Dr. M. SEHAILIA from Centre de Recherche Scientifique et Technique en Analyses Physico-Chimiques (CRAPC) unravel how hydroxychloroquine (HCQ, PLAQUENIL) interacts with the Spike Protein (SProtein) of SARS-CoV-2 virus responsible for COVID-19 outbreak and preventing its interaction with angiotensin-converting enzyme 2 (ACE2) protein residing on the surface of human cells.