Publications de la Division Santé : ABSTRACT DES ARTICLES SCIENTIFIQUES

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November 3, 2018  Publications de la Division Santé : ABSTRACT DES ARTICLES SCIENTIFIQUES 105

EXPRESSION OF ADENOSINE 5-MONOPHOSPHATE—ACTIVATED PROTEIN KINASE IN OVINE TESTIS (OVIS ARIES): IN VIVO REGULATION BY NUTRITIONAL STATE

  1. Taïbi, J. Dupont, Z. Bouguermouh, P. Froment, C. Ramé, A. Anane,
    Z. Amirat, F. Khammar

Animal Reproduction Science, 178 (2017) 9-22.

Keywords: Domestic ruminant, Die, Steroidogenesis, AMPK, Signal transduction

CATALYST-FREE ONE-POT SYNTHESIS OF CHROMENO IMIDAZOPYRIDINONES BY AN AZA-MICHAEL ADDITION/REARRANGEMENT/ HETEROCYCLIZATION TANDEM REACTION

  1. Lakhdari, O. Talhi, R. Hassaine, N. Taibi, R. F. Mendese, F. A. A. Paze, N. Bennamane, B. Nedjar-Kolli,  K. Bachari, A. M. S. Silva

Synlett, 29 (2018) 1437–1440.

SYNTHESIS AND RING TRANSFORMATION OF OXYGEN AND NITROGEN SPIRO BISHETEROCYCLES

  1. Talhi, D. C. G. A. Pinto, F. A. A Paz, M. Hamdi, A. M. S. Silva

Synlett, 26 (2015) 167–172.
Key words spiro bisheterocycles, oxygen and nitrogen heterocycles, bisnucleophiles, NMR, X-ray diffraction

ORGANOBASE CATALYZED 1,4-CONJUGATE ADDITION OF 4-HYDROXYCOUMARINON CHALCONES: SYNTHESIS, NMR AND SINGLE-CRYSTAL X-RAY DIFFRACTIONSTUDIES OF NOVEL WARFARIN ANALOGUES

  1. Talhi, J. A. Fernandes, D. C.G.A. Pinto, F. A. A Paz, A. M.S. Silva

Journal of Molecular Structure 1094 (2015) 13-21.

Keywords: Warfarin analogues,  Bicyclo[3.3.1]nonanes, 1,4-Conjugate addition,  Organobase catalysis, NMR, X-ray diffraction

A ONE-POT DIASTEREOSELECTIVE SYNTHESIS OF 2-[ARYL(HYDROXY)-METHYL]-6-METHYL2H-FURO[3,2-C]PYRAN-3,4-DIONES: CRYSTALLOGRAPHIC EVIDENCE FOR THE FURANONE RING CLOSURE

  1. Abdi, B. Boutemeur-Kheddis, M. Hamdi, O. Talhi, F.A. A Paz, G. Kirsch, A. M. S. Silva

Synlett, 26 (2015)  1749–1754.

Keywords furan-3-ones, pyran-2-ones, dehydroacetic acid, synthesis, organobase, 2NMRspectroscopy, single-crystal X-ray diffraction

ONE-POT SYNTHESIS OF NOVEL HIGHLY FUNCTIONALIZED FURAN-BASED POLYPHENOLICS

  1. L. C. Sousa, O. Talhi, D. H. A. Rocha, D. C. G. A. Pinto, F. A. A Paz, K. Bachari, G. Kirsch, A. M. S. Silva

Synlett,  26 (2015) 2724–2729.

Key words furan, polyphenols, 1,3-dicarbonyl compounds, 1,4-conjugate addition, ring transformation

MULTICOMPONENT SYNTHESIS OF 2[ARYL(ARYLAMINO)METHYL]FURO[3,2- C]PYRAN-3,4-DIONES AND DIASTEREOSELECTIVE FURAN RING OPENING TO (Z)-3-[3-ARYL-3-(ARYLAMINO)ACRYLOYL]-4-HYDROXYPYRAN-2-ONES

  1. Abdi, B. Boutemeur-Kheddis, M. Hamdi, O. Talhi,  K. Bachari,  G. Kirsch,  A. M. S. Silva

Synlett, 27 (2016)
Key words multicomponent reactions, furan-3-ones, pyran-2-ones, dehydroacetic acid, tautomerism

BIOLOGICAL ACTIVITIES AND PHENOLIC CONTENTS OF ARGANIA
SPINOSA L (SAPOTACEAE) LEAF EXTRACT

  1. Dakiche, M. Khali, A. K Abu-el-Haija, A. AlMaaytah and Q. A Al-Balas

Tropical Journal of Pharmaceutical Research, 15 (2016) 2563-2570.

Keywords: Argania spinosa, Polyphenols, Flavonoids, Antioxidant, Antibacterial, Cytotoxic

CATALYTIC ONE-POT DIASTEREOSELECTIVE MICHAEL-INITIATED RINGCLOSURE OF METHYL KETONES WITH 3-BROMOCHROMONES: SYNTHESIS OF CYCLOPROPA [B] CHROMANONES

  1. L. C. Sousa, O. Talhi, R. F. Mendes, F. A. A. Paz,
    K. Bachari, and A. M. S. Silva

Eur. J. Org. Chem, (2016) 3949–3958.

Keywords: Oxygen heterocycles · Cyclopropanes · Small ring systems · Fused-ring systems · Michael addition
Cyclization

ONE-POT SYNTHESIS OF BENZOPYRAN-4-ONES WITH CANCER PREVENTIVE AND THERAPEUTIC POTENTIAL

  1. Talhi, L. Brodziak-Jarosz, J. Panning, B. Orlikova, C. Zwergel, T. Tzanova, S. Philippot, D. C. G. A. Pinto, F. A. A. Paz,  C. Gerhäuser, T. P. Dick, C. Jacob,  M. Diederich,  D. Bagrel,  G. Kirsch,  and A. M. S. Silva

Eur. J. Org. Chem, (2016)  965–975.

Keywords: Medicinal chemistry · Drug discovery · Anticancer agents · Oxygen heterocycles · Domino reactions · Michael addition · Antioxidants

DIBENZO [B, E][1,4]DIAZEPIN-1-ONES AND THEIR RING-OPENED DERIVATIVES: REVISITED SYNTHESIS, 2D NMR AND CRYSTAL STRUCTURE

  1. Cherfaoui, H. Lakhdari, N. Bennamane, R. Ameraoui, O. Talhi,  F. A. A. Paz,  K. Bachari,  G. Kirsch,  K. Nejar-Bellara,  A. M. S. Silva

Synlett, 28 (2017) 2247–2252.

Key words 3-[(2-aminoaryl) amino]dimedones, carbonylated electrophiles, dibenzo[b,e][1,4]diazepin-1-ones, reaction mechanism, 2D NMR, single-crystal X-ray diffraction

SYNTHETIC APPROACH TOWARD HETEROCYCLIC HYBRIDS OF   [1, 2, 4] TRIAZOLO [3, 4-B][1,3,4]THIADIAZINES

  1. Lechani, M. Hamdi, B. Kheddis-Boutemeur,  O. Talhi,  Y. Laichi,  K. Bachari,  A. M. S. Silva

Synlett, 29 (2018) 1502–1504.

Key words triazolothiadiazines, triazolylphenol, bromomethyl ketones, polycycles, heterocycles, cyclization

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